| Объем | 100 мкл |
| Синонимы | TATA binding factor, TATA sequence-binding protein, TATA-box binding protein, TATA-box factor, TFIID |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P20226 |
| Иммуноген | Synthesized peptide derived from internal of human TBP. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.<br/><br/>Peterson M.G., Science 248:1625-1630(1990).<br/>Mungall A.J., Nature 425:805-811(2003).<br/>Gangloff Y.G., Mol. Cell. Biol. 21:5109-5121(2001).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Isotype/Loading Controls,Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using TBP antibody.
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Наименование: TBP Antibody.