TNFRSF1A AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CD120a, TBPI, TNF-RI, TNFAR, TNFR1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P19438 | | Иммуноген | Synthesized peptide derived from Internal of human TNF receptor-1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.<br/><br/>Jennifer Adjodha, AACR Meeting Abstracts, Apr 2006, 2006: 1028. <br/>Kewu Huang, J Appl Physiol, Apr 2007, 102: 1632 - 1639. <br/>Kiyoshi Asada, AACR Meeting Abstracts, Apr 2005, 2005: 202. <br/>Elaine K Green, J. Med. Genet., Aug 2000, 37: 581.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Cell biology,Immunology,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TNF receptor-1 antibody.
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Наименование: TNFRSF1A Antibody.