| Объем | 100 мкг |
| Синонимы | T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein) (zSCL), tal1, scl tal-1 |
| Клональность | Polyclonal Antibody |
| Организм | Zebrafish |
| uniprot | O93507 |
| Иммуноген | Recombinant Zebrafish T-cell acute lymphocytic leukemia protein 1 homolog protein (1-324AA) |
| Источник | Rabbit |
| Видовая специфичность | Zebrafish |
| Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
| Примечание | Transcription factor that plays a pivotal role in hemopoietic and endothelial development, acting synergistically with lmo2 and downstream of clo. Specifies mesodermal precursors to a hemangioblast cell fate. Hemangioblasts are bipotential precursors of blood and endothelium, and in the absence of hemopoietic induction cues such as gata1, tal1/scl-lmo2-induced hemangioblasts differentiate into endothelial cells. Isoform alpha and isoform beta are redundant for the initiation of primitive hemopoiesis but have distinct roles in the regulation of primitive erythroid differentiation and definitive hemopoietic stem cell specification, most likely due to differences in expression levels. Specification of definitive hemopoietic stem cells requires isoform beta. DNA binding is required for erythroid maturation, but not for its other hemopoietic functions. Endothelial roles include development of the dorsal aorta, the site of definitive hemopoiesis in the embryo. Required for angiogenesis but not angioblast specification. Has an additional role in endocardium formation during heart development. May play a role in central nervous system development. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | T-cell acute lymphocytic leukemia protein 1 homolog |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Zebrafish tissue 20?g, 10?g
All lanes: tal1 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 36, 23 kDa
Observed band size: 36 kDa
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Наименование: tal1 Antibody.