| Объем | 100 мкл |
| Синонимы | SFR7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q16629 |
| Иммуноген | Synthesized peptide derived from internal of human SFRS7. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.<br/><br/>Cavaloc Y., EMBO J. 13:2639-2649(1994).<br/>Popielarz M., J. Biol. Chem. 270:17830-17835(1995).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells, using SFRS7 antibody.
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