| Объем | 100 мкг |
| Синонимы | Polymerase cofactor VP35, VP35 |
| Клональность | Polyclonal Antibody |
| Организм | Reston ebolavirus |
| uniprot | Q91DE0 |
| Иммуноген | Recombinant Reston ebolavirus Polymerase cofactor VP35 protein (1-329AA) |
| Источник | Rabbit |
| Видовая специфичность | Reston ebolavirus |
| Применение | ELISA |
| Примечание | Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex. Prevents establishment of cellular antiviral state by blocking virus-induced phosphorylation and activation of interferon regulatory factor 3 (IRF3), a transcription factor critical for the induction of interferons alpha and beta. This blockage is produced through the interaction with and inhibition host IKBKE and TBK1 producing a strong inhibition of the phosphorylation and activation of IRF3. Also inhibits the antiviral effect mediated by the interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: VP35 Antibody.