VAV1 (Ab-174) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Proto-oncogene vav, VAV1, VAV, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P15498 | | Иммуноген | Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D). | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.<br/><br/>Ana V. Miletic, J. Biol. Chem., Dec 2006, 281: 38257 - 38265.<br/>Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003, 23: 6291 - 6299.<br/>Vered Schapira, Cancer Res., Jun 2006, 66: 6183 - 6191.<br/>Maya Groysman, J. Biol. Chem., Dec 2002, 277: 50121 - 50130.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using VAV1 (Ab-174) antibody.
 | Western blot analysis of extracts from JK cells (Lane 2), using VAV1 (Ab-174) antiobdy. The lane on the left is treated with synthesized peptide.
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