SNCB AntibodyСпецификация| Объем | 100 мкл | | Синонимы | SYUB, beta-synuclein, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q16143 | | Иммуноген | Synthesized peptide derived from human Synuclein beta antibody. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.<br/><br/>Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011. <br/>Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629. <br/>Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335. <br/>Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using Synuclein ? antibody.
 | Immunofluorescence analysis of A549 cells, using Synuclein ? antibody.
 | Western blot analysis of extracts from HeLa cells, using Synuclein ? antibody.
 | Western blot analysis of extracts from 293 cells (Lane 2) and cos-7 cells (Lane 3), using Synuclein ? antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: SNCB Antibody.