SMAD2 Monoclonal AntibodyСпецификация| Объем | 100 мкл | | Синонимы | hMAD 2, hMAD-2, hSMAD2, JV18 1, JV18, JV18, JV18-1, JV181, MAD, MAD, MAD homolog 2, MAD Related Protein 2, Mad-related protein 2, MADH2, MADR2, MGC22139, MGC34440, Mothers Against Decapentaplegic Homolog 2, Mothers Against Decapentaplegic Homolog 2, | | Видовая специфичность | Human | | Uniport ID | Q15796 | | Иммуноген | Purified recombinant human SMAD2 protein fragments expressed in E.coli. | | Источник | Mouse | | Видовая специфичность 1 | Human | | Применение | ELISA,WB,ICC,Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200 | | Примечание | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. | | Изотип | IgG1 | | Метод очистки | Affinity purified | | Коньюгат | Non-conjugated | | Буффер | Ascites | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Signal transduction,Stem cells | | Станица на сайте производителя | ссылка | | | |
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Наименование: SMAD2 Monoclonal Antibody.