| Объем | 50 мкл |
| Синонимы | runt-related transcription factor 1, translocated to, 1 (cyclin D-related) |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q06455 |
| Иммуноген | Synthetic peptide of human RUNX1T1 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Примечание | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA113088(RUNX1T1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: RUNX1T1 Antibody.