SCN5A AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CIN5, HH1, SCN5A, Sodium channel protein, cardiac muscle alpha-subunit | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q14524 | | Иммуноген | Synthesized peptide derived from human sodium channel. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.<br/><br/>Sebastian K.G. Maier, Circulation, Mar 2004, 109: 1421 - 1427. <br/>T.R. Cummins, Neurology, Jan 2003, 60: 224 - 229. <br/>Christopher A. Ahern, Circ. Res., May 2005, 96: 991 - 998. <br/>Jyoti Dhar Malhotra, Circulation, Mar 2001, 103: 1303 - 1310. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Cardiovascular | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HuvEc cells, using Sodium Channel-pan antibody.
 | Immunohistochemical analysis of paraffin-embedded human heart tissue using Sodium Channel-pan antibody.
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Наименование: SCN5A Antibody.