SMC5 Antibody, FITC conjugated

Спецификация

Объем	100 мкг
Синонимы	Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5), SMC5, KIAA0594 SMC5L1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8IY18
Иммуноген	Recombinant Human Structural maintenance of chromosomes protein 5 protein (296-403AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Structural maintenance of chromosomes protein 5
Области исследований	Epigenetics and Nuclear Signaling, Cell biology
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA810294LC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: SMC5 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).