| Объем | 50 мкг |
| Синонимы | TAR DNA-binding protein 43 (TDP-43), TARDBP, TDP43 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13148 |
| Иммуноген | Recombinant Human TAR DNA-binding protein 43 protein (1-396AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | TAR DNA-binding protein 43 |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Microbiology |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: TARDBP Antibody, Biotin conjugated.