SLC38A9 Antibody, FITC conjugated

Спецификация

Объем	100 мкг
Синонимы	Sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11), SLC38A9, URLC11
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8NBW4
Иммуноген	Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Sodium-coupled neutral amino acid transporter 9
Области исследований	Metabolism, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA836713LC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: SLC38A9 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).