| Объем | 50 мкл |
| Синонимы | Ring finger protein 126 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9BV68 |
| Иммуноген | Synthetic peptide of human RNF126 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Примечание | The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF126 interacts with p21 and RNF126 over-expression increased p21 protein ubiquitination in an E3 ligase activity-dependent manner. RNF126 knockdown induced loss of cell viability in MDA-MB-231 and PC-3 can be partially rescued by depletion of p21. RNF126 stable knockdown in PC3 inhibited tumor growth in SCID mice. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA059841(RNF126 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA059841(RNF126 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
 |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Jurkat cells, K562 cells, Primary antibody: CSB-PA059841(RNF126 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
 |
| | |
Наименование: RNF126 Antibody.