| Объем | 100 мкл |
| Синонимы | SH2 domain-containing adapter protein B, SHB, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q15464 |
| Иммуноген | Synthesized peptide derived from C-terminal of human SHB. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.<br/><br/>Welsh M., Oncogene 9:19-27(1994).<br/>Humphray S.J., Nature 429:369-374(2004).<br/>Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Developmental biology,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEc cells, using SHB antibody.
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Наименование: SHB Antibody.