| Объем | 100 мкл |
| Синонимы | E3 ubiquitin-protein ligase RAD18, hHR18, hRAD18, postreplication repair protein hRAD18p, Postreplication repair protein RAD18 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NS91 |
| Иммуноген | Synthesized peptide derived from internal of human RAD18. |
| Источник | Rabbit |
| Видовая специфичность | Human, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.<br/><br/>Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).<br/>Xin H., Nucleic Acids Res. 28:2847-2854(2000).<br/>Muzny D.M., Nature 440:1194-1198(2006).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from LOVO cells, HepG2 cells and K562 cells, using RAD18 antibody.
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Наименование: RAD18 Antibody.