RCC1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CHC1, Cell cycle regulatory protein, Regulator of chromosome condensation, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P18754 | | Иммуноген | Synthesized peptide derived from human RCC1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.<br/><br/>M Dasso, Mol. Cell. Biol., Aug 1992, 12: 3337 - 3345. <br/>Hoi Yeung Li, J. Cell Biol., Mar 2003, 160: 635. <br/>Michael E. Nemergut, Science, May 2001, 292: 1540. <br/>Ian Cushman, Mol. Biol. Cell, Jan 2004, 15: 245. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RCC1 antibody.
 | Western blot analysis of extracts from LOVO cells, using RCC1 antibody.
 | Western blot analysis of extracts from HepG2 cells (Lane 2), cells (Lane 3) and cells (Lane 4), using RCC1 antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: RCC1 Antibody.