| Объем | 100 мкл |
| Синонимы | KS6B1, P70-S6K, RPS6KB1, S6K, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P23443 |
| Иммуноген | Peptide sequence around aa.419~423 (P-R-T-P-V) derived from Human p70 S6 Kinase. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
| Примечание | Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.<br/><br/>Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497<br/>An WL, et al. (2003) Am J Pathol. 163(2): 591-607.<br/>Le XF, et al. (2003) Oncogene.22(4): 484-97<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells using p70 S6 Kinase(Ab-421) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
 |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase(Ab-421) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 |
| | |
Наименование: RPS6KB1 (Ab-421) Antibody.