PTPN11 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q06124 | | Иммуноген | Synthesized peptide derived from human SH-PTP2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.<br/><br/>T Noguchi, Mol. Cell. Biol., Oct 1994, 14: 6674 - 6682. <br/>U Dechert, J. Biol. Chem., Feb 1994, 269: 5602 - 5611. <br/>Hiroshi Ohnishi, J. Biol. Chem., Oct 1996, 271: 25569. <br/>Tetsuya Noguchi, J. Biol. Chem., Nov 1996, 271: 27652. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using SH-PTP2 antibody.
 | Western blot analysis of extracts from COS7 cells, using SH-PTP2 antibody.
 | Western blot analysis of extracts from JK cells (Lane 2), using SH-PTP2 antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: PTPN11 Antibody.