PTCH1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DROSOPHILA HOMOLOG OF 1, patched homolog (Drosophila), | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13635 | | Иммуноген | Synthesized peptide derived from human Patched. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.<br/><br/>Trudy G. Oliver, Development, May 2005, 132: 2425 - 2439. <br/>Florence Brellier, Cancer Res., Apr 2004, 64: 2699 - 2704. <br/>Heidi Hahn, J. Biol. Chem., May 1996, 271: 12125. <br/>RL Johnson, Development, Dec 1995, 121: 4161. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Cancer,Cell biology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using Patched antibody.
 | Western blot analysis of extracts from mouse muscle cells, using Patched antibody.
 | Western blot analysis of extracts from 3T3 cells (Lane 2) and HepG2 cells (Lane 3), using Patched antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: PTCH1 Antibody.