| Объем | 100 мкл |
| Синонимы | Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2), PRMT2, HMT1 HRMT1L1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P55345 |
| Иммуноген | Recombinant Human Protein arginine N-methyltransferase 2 protein (1-300AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:2000, IHC:1:20-1:200 |
| Примечание | Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PRMT2 antibody at 4µg/ml + HL60 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50, 32, 38, 33, 34, 26, 32 kDa
Observed band size: 50 kDa
 |
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA018732ESR1HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018732ESR1HU at dilution of 1:100
 |
| | |