| Объем | 50 мкл |
| Синонимы | Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B), PTPN1, PTP1B |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P18031 |
| Иммуноген | Recombinant Human Tyrosine-protein phosphatase non-receptor type 1 protein (281-435AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, Recommended dilution: WB:1:500-1:2000 |
| Примечание | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cardiovascular, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PTPN1 antibody at 2µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: A431 whole cell lysate
Lane 3: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
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Наименование: PTPN1 Antibody.