| Объем | 100 мкл |
| Синонимы | Protein arginine methyltransferase 7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NVM4 |
| Иммуноген | Fusion protein of human PRMT7 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Примечание | Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Gel: 10%SDS-PAGE, Lysate: 50 ?g, Lane: 231 cells, Primary antibody: CSB-PA559119(PRMT7 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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