RAB31 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Ras-related protein Rab-31, Ras-related protein Rab-22B, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13636 | | Иммуноген | Synthesized peptide derived from internal of human RAB31. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.<br/><br/>Chen D., Gene 174:129-134(1996) [PubMed: 8863739].<br/>Bao X.,Eur. J. Biochem. 269:259-271(2002) [PubMed: 11784320].<br/>Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells and HepG2 cells, using RAB31 antibody.
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Наименование: RAB31 Antibody.