RPA1 Monoclonal AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Dmrpa1, Drosophila Replication Protein A, DRPA, HSSB, Human single stranded DNA binding protein, MST075, MSTP075, p70, REPA1, Replication factor A, Replication factor A protein 1, Replication protein A 70 kDa DNA-binding subunit, | | Видовая специфичность | Human | | Uniport ID | P27694 | | Иммуноген | Purified recombinant human RPA70 protein fragments expressed in E.coli. | | Источник | Mouse | | Видовая специфичность 1 | Human,Monkey,Mouse,Rat | | Применение | ELISA,WB,ICC,IP,Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200IP:1:200-1:2000 | | Примечание | Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair,it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. | | Изотип | IgG2a | | Метод очистки | Affinity purified | | Коньюгат | Non-conjugated | | Буффер | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Области исследований | Epigenetics and Nuclear Signaling | | Станица на сайте производителя | ссылка | | | |
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Наименование: RPA1 Monoclonal Antibody.