PRKCZ (Ab-410) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | PKC2, PKC-ZETA, PRKCZ | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q05513 | | Иммуноген | Peptide sequence around aa. 408~412 ( T-S-T-F-C) derived from PKCz | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.<br/><br/>Parmentier JH, et al. (2004) BMC Cell Biol, 5: 4.<br/>Castrillo A, et al. (2003) Mol Cell Biol, 23(4): 1196-1208.<br/>Paramio JM, et al. ( 2001) Mol Cell Biol, 21(21): 7449-7459.<br/>Braiman L, et al. (2001) Mol Cell Biol, 21(22): 7852-7861.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from 293 cells and Hela using PKCz(Ab-410) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKCz(Ab-410) antibody.
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