PRA1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | pH-regulated antigen PRA1 (58 kDa fibrinogen-binding mannoprotein), PRA1, FBP1 | | Клональность | Polyclonal Antibody | | Организм | Candida albicans | | uniprot | P87020 | | Иммуноген | Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA) | | Источник | Rabbit | | Видовая специфичность | Candida albicans | | Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 | | Примечание | Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | pH-regulated antigen PRA1 | | Области исследований | N/A | | Ссылка на страницу на сайте производителя | ссылка | Western Blot
Positive WB detected in Recombinant protein
All lanes: PRA1 antibody at 4.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
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Наименование: PRA1 Antibody.