Phospho-TGFBR2 (Ser225/250) Antibody

Спецификация

Объем	100 мкл
Синонимы	TGF-betaR2, TGFR2, kinase TGF-beta-R2,
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P37173
Иммуноген	Peptide sequence around phosphorylation site of Serine 225/250(D-R-S(p)-D-I) derived from Human TGF beta Receptor II.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, IHC,IHC:1:50-1:100
Примечание	<p>Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. <br/><br/>RC Tripathi, Invest. Ophthalmol. Vis. Sci., Jan 1993, 34: 260. <br />N Chegini, Endocrinology, Jul 1994, 135: 439. <br />GW Mulheron, Endocrinology, Dec 1992, 131: 2609<br /></p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Ser225/250
Области исследований	Signal transduction,Stem cells
Ссылка на страницу на сайте производителя	ссылка
Immunohistochemical analysis of paraffin-embedded human brain tissue using TGF ? Receptor II (Phospho-Ser225/250) antibody (left)or the same antibody preincubated with blocking peptide (right).

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA911102
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-TGFBR2 (Ser225/250) Antibody. Примечание: дополнительная информация (на английском языке).