| Объем | 100 мкл |
| Синонимы | hMAD-2, JV18, JV18-1, MAD, hSMAD2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q15796 |
| Иммуноген | Peptide sequence around phosphorylation site of Serine 465(C-S-S(p)-M-S) derived from Human Smad2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.<br/><br/>Riggins G.J., Nat. Genet. 13:347-349(1996).<br />Zhang Y., Nature 383:168-172(1996).<br />Eppert K., Cell 86:543-552(1996).<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser465 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells using Smad2 (Phospho-Ser465) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-SMAD2 (Ser465) Antibody.