RFX6 Antibody, Biotin conjugatedСпецификация| Объем | 100 мкг | | Синонимы | DNA-binding protein RFX6 (Regulatory factor X 6) (Regulatory factor X domain-containing protein 1), RFX6, RFXDC1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q8HWS3 | | Иммуноген | Recombinant Human DNA-binding protein RFX6 protein (1-260AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin (PubMed:20148032, PubMed:25497100). Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes (PubMed:20148032). Involved in glucose-stimulated insulin secretion by promoting insulin and L-type calcium channel gene transcription (PubMed:25497100). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA812809LD01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: RFX6 Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
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