| Объем | 100 мкл |
| Синонимы | DNA-directed RNA polymerase I 135 kDa polypeptide, DNA-directed RNA polymerase I 135kDa polypeptide, DNA-directed RNA polymerase I subunit RPA2, FLJ10816, FLJ21921 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9H9Y6 |
| Иммуноген | Synthesized peptide derived from C-terminal of human POLR1B. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft By similarity.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Hillier L.W., Nature 434:724-731(2005).<br/>Miller G., EMBO J. 20:1373-1382(2001).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat/NIH-3T3 cells, using POLR1B antibody.
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Наименование: POLR1B Antibody.