Phospho-PRKCD (Ser645) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | KPCD, PKC-delta, PRKCD, kinase PKC-delta, nPKC-delta | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q05655 | | Иммуноген | Peptide sequence around phosphorylation site of serine 645 (R-L-S(p)-Y-S) derived from Human PKCd. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 | | Примечание | This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin. <br/><br/>Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab , 285: E1081 - E1088. <br/>Ling Zhang, et,al. (2004) J. Biol. Chem , 279: 28315 - 28319. <br/>Kristof Van Kolen et,al. (2006) FEBS J , 273: 1843 - 1854. <br/>Martin Villalba, et,al. (2002) J. Cell Biol , 157: 253. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser645 | | Области исследований | Neuroscience,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from PC12 cells untreated or treated with PMA using PKCd(Phospho-Ser645) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PKCd(Phospho-Ser645) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA019964 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-PRKCD (Ser645) Antibody.
Примечание: дополнительная информация (на английском языке). |
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