Phospho-EPOR (Tyr368) Antibody

Спецификация

Объем	100 мкл
Синонимы	EPO R, EPO-R, epor,
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P19235
Иммуноген	Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	<p>Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.<br/><br/>Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307 <br />Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97 <br />Zhang YL, et al. (2009) Mol Cell 33, 266-74 </p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Tyr368
Области исследований	Cardiovascular,Immunology,Signal transduction,Stem cells
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from K562 tissue using Epo-R (Phospho-Tyr368) antibody.The lane on the right is treated with the antigen-specific peptide.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA598485
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-EPOR (Tyr368) Antibody. Примечание: дополнительная информация (на английском языке).