Phospho-CSNK2A1 (Thr360/Ser362) Antibody

Спецификация

Объем	100 мкл
Синонимы	CKII, CK2A1, CSNK2A1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P68400
Иммуноген	Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.<br/><br/>Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001) <br/>Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)<br/>Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)<br/>Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000) <br/>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Thr360/Ser362
Области исследований	Cell biology,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot of CK2a(Phospho- Thr360/Ser362) antibody and CK2a antibody in vitro kinase assay. Both purified ERK2 and CK2 were used. CK2a(Phospho-Thr360/Ser362) antibody could recognize ERK2 phosphorylated wild type CK2a and CK2a when Ser362 was mutated to alanine .

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA253823
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-CSNK2A1 (Thr360/Ser362) Antibody. Примечание: дополнительная информация (на английском языке).