Phospho-NFKB2 (Ser872) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DNA-binding factor KBF2, Lymphocyte translocation chromosome 10, Lyt10, Nuclear factor NF-kappa-B p100 subunit, Oncogene Lyt-10 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q00653 | | Иммуноген | Peptide sequence around phosphorylation site of serine872(S-Q-S(p)-V-E) derived from Human NF-κB p100 . | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. <br/><br/>Qu Z, Qing G, Rabson A, Xiao G (2004) J Biol Chem 279, 44563-72 . Xiao G, Fong A, Sun SC (2004) J Biol Chem 279, 30099-105 .</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser872 | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from RAW264.7 cells treated with EGF using Phospho-NF-?B p100 (Ser872) antibody.The lane on the right is treated with the antigen-specific peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA163283 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-NFKB2 (Ser872) Antibody.
Примечание: дополнительная информация (на английском языке). |
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