| Объем | 100 мкл |
| Синонимы | P531, TP53B, TP53BP1, TRP53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q12888 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 25 (E-D-S(p)-Q-P) derived from Human 53BP1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser25 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using 53BP1 (Phospho-Ser25) antibody. The picture on the right is treated with the synthesized peptide.
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Immunofluorescence analysis of NIH/3T3 cells, using 53BP1 (Phospho-Ser25) antibody. The picture on the right is treated with the synthesized peptide.
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Наименование: Phospho-TP53BP1 (Ser25) Antibody.