Phospho-ABL1 (Tyr204) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | p150, c-ABL, EC 2.7.10.2, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P00519 | | Иммуноген | Peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y(p)-V-S) derived from Human c-Abl. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation), ANXA1 (involved in membrane anchoring), DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling), or MAPT and PXN (microtubule-binding proteins). <br /><br />Meyn MA, et al. (2006) J Biol Chem 281, 30907-16 <br />Steen H, et al. (2003) Mol Cell Proteomics 2, 138-45<br />Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr204 | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) antibody.The lane on the right is treated with the antigen-specific peptide.
 | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA984556 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-ABL1 (Tyr204) Antibody.
Примечание: дополнительная информация (на английском языке). |
|
