Phospho-PTK2 (Tyr861) Antibody

Спецификация

Объем	100 мкл
Синонимы	FADK 1, FAK1, PTK2
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q05397
Иммуноген	Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P) derived from Human FAK.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.<br/><br/>Shi Q, et al. (2003) Mol Biol Cell, 14(10): 4306-15.<br/>Vadlamudi RK, et al. (2003) FEBS Lett, 543(1-3): 76-80.<br/>Eliceiri BP, et al. (2002) J Cell Biol Apr 01, 157(1): 149-60.<br/>Abu-Ghazaleh R, (2001) et al. Biochem J, 360(Pt 1): 255-64.<br/>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Tyr861
Области исследований	Cancer,Cardiovascular,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from HT29 cells untreated or treated with EGF using FAK(Phospho-Tyr861) Antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA911015
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-PTK2 (Tyr861) Antibody. Примечание: дополнительная информация (на английском языке).