| Объем | 100 мкл |
| Синонимы | HCLS1, LCKBP1, Hematopoietic cell- specific LYN substrate 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P14317 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 . |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression. <br/><br/>Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).<br />Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.<br />Ota T., Nat. Genet. 36:40-45(2004).<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr397 |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JK cells (Lane 2), using HS1 (Phospho-Tyr397) Antibody.The lane on the left is treated with antigen-specific peptide.
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Наименование: Phospho-HCLS1 (Tyr397) Antibody.