| Объем | 100 мкл |
| Синонимы | Cadherin-associated protein, Alpha E-catenin, NY-REN-13 antigen |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P35221 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 641 (D-D-S(p)-D-F) derived from Human a-catenin. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation. <br /><br />Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765 <br />Drees, F. et al. (2005) Cell 123, 903-915. <br />Yamada, S. et al. (2005) Cell 123, 889-901. <br />Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser641 |
| Области исследований | Cancer,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela cells untreated or treated with starvation using a-catenin(Phospho-Ser641) antibody.
 |
Western blot analysis of extracts from HT29 cells, treated with serum or calf intestinal phosphatase (CIP), using ?-catenin (Phospho-Ser641) Antibody.
 |
| | |
Наименование: Phospho-CTNNA1 (Ser641) Antibody.