PARP1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | poly (ADP-ribose) polymerase 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P09874 | | Иммуноген | Synthetic peptide of human PARP1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 | | Примечание | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA436053(PARP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA436053(PARP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-3: Hela cells, K562 cells, Jurkat cells, Primary antibody: CSB-PA436053(PARP1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
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Наименование: PARP1 Antibody.