| Объем | 100 мкл |
| Синонимы | Partitioning-defective 3 homolog, PARD-3, PAR-3, Atypical PKC isotype-specific-interacting protein, ASIP |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8TEW0 |
| Иммуноген | Synthesized peptide derived from internal of human PARD3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.<br/><br/>Joberty G., Nat. Cell Biol. 2:531-539(2000).<br/>Fang C.M., Cell Res. 11:223-229(2001).<br/>Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using PARD3 antibody.
 |
Immunofluorescence analysis of HepG2 cells, using PARD3 antibody.
 |
| | |
Наименование: PARD3 Antibody.