| Объем | 100 мкл |
| Синонимы | HECH, HP1 gamma, HP1Hs-gamma, chromobox 3, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13185 |
| Иммуноген | Peptide sequence around phosphorylation site of Serine 93(R-L-S(p)-L-S) derived from Human HP1gamma . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.<br/><br/>Ye Q., J. Biol. Chem. 271:14653-14656(1996).<br />Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.<br />Koike N., FEBS Lett. 467:17-21(2000)</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser93 |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells treated with forskolin using HP1? (Phospho-Ser93) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-CBX3 (Ser93) Antibody.