| Объем | 100 мкл |
| Синонимы | BCL2-like protein 11, BCL2L11, BOD, Bcl-2 related ovarian death protein, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O43521 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G) derived from Human BIM. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:200 |
| Примечание | Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis<br/><br/>Fukazawa H, et al. (2004) Mol Cancer Ther , 3(10): 1281-1288<br/>Luciano F, et al. (2003) Oncogene , 22(43): 6785-6793<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser69 |
| Области исследований | Neuroscience,Cancer,Cell biology,Immunology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BIM(Phospho-Ser69) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed Hela cells using BIM(Phospho-Ser69) Antibody.
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Наименование: Phospho-BCL2L11 (Ser69) Antibody.