| Объем | 100 мкл |
| Синонимы | activator of RNA decay, ARD-1, ARD1, EC 3.1.4.-, NIPP1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q12972 |
| Иммуноген | Synthesized peptide derived from internal of human PPP1R8. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform doesnot inhibit PP-1. May be implicated in mRNA splicing.<br/><br/>Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994).<br/>Van Eynde A., Eur. J. Biochem. 261:291-300(1999).<br/>Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.<br/><br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using PPP1R8 antibody.
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Наименование: PPP1R8 Antibody.