| Объем | 100 мкг |
| Синонимы | Protein P [Includes: DNA-directed DNA polymerase (EC 2.7.7.7), RNA-directed DNA polymerase (EC 2.7.7.49), Ribonuclease H (EC 3.1.26.4)], P |
| Клональность | Polyclonal Antibody |
| Организм | Hepatitis B virus genotype A2 subtype adw2 |
| uniprot | P17100 |
| Иммуноген | Recombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA) |
| Источник | Rabbit |
| Видовая специфичность | Hepatitis B virus genotype A2 subtype adw2 |
| Применение | ELISA |
| Примечание | Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: P Antibody.