Phospho-AURKC (Thr236/202) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | AIE1, AIE2, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 1, Aurora/Ipl1/Eg2 protein 2, EC 2.7.11.1, STK13, STKD, Serine/threonine protein kinase 13, kinase AIK3 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UQB9 | | Иммуноген | Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Thr236/202 | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human brain tissue using AurB/C (Phospho-Thr236/202) antibody. The picture on the right is treated with the synthesized peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA238732 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: Phospho-AURKC (Thr236/202) Antibody. Примечание: дополнительная информация (на английском языке). |
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