| Объем | 100 мкл |
| Синонимы | peptidyl arginine deiminase, type IV |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UM07 |
| Иммуноген | Fusion protein of human PADI4 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:100-1:500, IHC:1:25-1:100 |
| Примечание | This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA266740(PADI4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA266740(PADI4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
 |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: A431 cells, Primary antibody: CSB-PA266740(PADI4 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
 |
| | |