MECP2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | methyl CpG binding protein 2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P51608 | | Иммуноген | Fusion protein of human MECP2 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:100-1:300 | | Примечание | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA440474(MECP2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA440474(MECP2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse lung tissue, Primary antibody: CSB-PA440474(MECP2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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Наименование: MECP2 Antibody.