MCM5 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CDC46, DNA replication licensing factor MMP-11, minichromosome maintenance deficient protein 5, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P33992 | | Иммуноген | Synthesized peptide derived from human MMP-11 antibody. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity By similarity. Interacts with MCMBP.<br/><br/>Robert A. Sclafani, Genetics, May 2002, 161: 47. <br/>Marylynn Snyder, PNAS, Oct 2005, 102: 14539 - 14544. <br/>Christopher J. DaFonseca, PNAS, Mar 2001, 98: 3034. <br/>Cathleen M. Lake, Genetics, Jun 2007, 10.1534. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-11 antibody.
 | Immunofluorescence analysis of A549 cells, using MMP-11 antibody.
 | Western blot analysis of extracts from A549 cells, using MMP-11 antibody.
 | Western blot analysis of extracts from HepG2 cells (Lane 2) and HeLa cells (Lane 3), using MMP-11 antiobdy. The lane on the left is treated with systhesized peptide.
 | | | |
Информация для заказа |
Наименование: MCM5 Antibody.